How a long-forgotten virus could help us solve the antibiotics crisis | Alexander Belcredi

Viruses have a bad reputation — but some of them could one day save your life, says biotech entrepreneur Alexander Belcredi. In this fascinating talk, he introduces us to phages, naturally-occurring viruses that hunt and kill harmful bacteria with deadly precision, and shows how these once-forgotten organisms could provide new hope against the growing threat of antibiotic-resistant superbugs.

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People can Inherit Mitochondrial DNA from Both Parents | SciShow News

Earlier this week, a team of researchers announced that they’d made a discovery about how we inherit mitochondrial DNA from our parents that could change what we know about not only disease inheritance, but human history as a whole.

Hosted by: Hank Green

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Sources:
http://www.pnas.org/cgi/doi/10.1073/pnas.1810946115
https://ghr.nlm.nih.gov/primer/basics/gene
https://ghr.nlm.nih.gov/mitochondrial-dna#definition
http://hihg.med.miami.edu/code/http/modules/education/Design/Print.asp?CourseNum=2&LessonNum=4
https://www.zmescience.com/other/science-abc/about-mitochondrial-dna-42423/
https://www.scientificamerican.com/article/how-do-researchers-trace/
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/nuclear-dna
https://www.pbs.org/wgbh/nova/article/dads-mitochondrial-dna/
http://www.mitoaction.org/guide/the-diagnosis-process
https://www.sciencedirect.com/science/article/pii/S0169534702000095
https://www2.palomar.edu/anthro/homo2/mod_homo_4.htm

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The key to a better malaria vaccine | Faith Osier

The malaria vaccine was invented more than a century ago — yet each year, hundreds of thousands of people still die from the disease. How can we improve this vital vaccine? In this informative talk, immunologist and TED Fellow Faith Osier shows how she’s combining cutting-edge technology with century-old insights in the hopes of creating a new vaccine that eradicates malaria once and for all.

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Why the hospital of the future will be your own home | Niels van Namen

Nobody likes going to the hospital, whether it’s because of the logistical challenges of getting there, the astronomical costs of procedures or the alarming risks of complications like antibiotic-resistant bacteria. But what if we could get the lifesaving care provided by hospitals in our own homes? Health care futurist Niels van Namen shows how advances in technology are making home care a cheaper, safer and more accessible alternative to hospital stays.

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How to create a world where no one dies waiting for a transplant | Luhan Yang

For nearly half a century, scientists have been trying to create a process for transplanting animal organs into humans, a theoretical dream that could help the hundreds of thousands of people in need of a lifesaving transplant. But the risks, specifically of transmitting the PERV virus from pigs to humans, have always been too great, stalling research — until now. In a mind-blowing talk, geneticist Luhan Yang explains a breakthrough: using CRISPR, a technique for editing genes, she and her colleagues have created pigs that don’t carry the virus, opening up the possibility of safely growing human-transplantable organs in pigs. Learn more about this cutting-edge science and how it could help solve the organ shortage crisis.

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design — plus science, business, global issues, the arts and more.

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How data is helping us unravel the mysteries of the brain | Steve McCarroll

Geneticist Steve McCarroll wants to make an atlas of all the cells in the human body so that we can understand in precise detail how specific genes work, especially in the brain. In this fascinating talk, he shares his team’s progress — including their invention of “Drop-seq,” a technology that allows scientists to analyze individual cells at a scale that was never before possible — and describes how this research could lead to new ways of treating mental illnesses like schizophrenia.

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design — plus science, business, global issues, the arts and more.

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6 Dangerous Diseases Hiding in U.S. Backyards

Microbes are all around us, on everything we touch, drink, or eat. While most microbes can’t hurt us, you don’t have to go much farther than your own backyard to find some that really can!

Hosted by: Olivia Gordon

Head to https://scishowfinds.com/ for hand selected artifacts of the universe!
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Sources:
Plague
https://www.britannica.com/event/Black-Death
https://www.ncbi.nlm.nih.gov/pubmed/22405453
https://www.cdc.gov/plague/maps/index.html
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6007a1.htm
https://www.cdc.gov/plague/symptoms/index.html
https://www.ncbi.nlm.nih.gov/pubmed/21756031
https://www.ncbi.nlm.nih.gov/pubmed/24484490
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173816/
http://www.who.int/news-room/fact-sheets/detail/plague
https://www.ncbi.nlm.nih.gov/pubmed/20158332
https://www.usgs.gov/news/oral-plague-vaccine-helps-reduce-outbreaks-prairie-dog-colonies

Sin Nombre Virus
https://www.cdc.gov/hantavirus/outbreaks/history.html
https://www.cdc.gov/hantavirus/rodents/index.html
https://www.cdc.gov/hantavirus/surveillance/annual-cases.html
https://www.ncbi.nlm.nih.gov/pubmed/24867065
https://www.cdc.gov/hantavirus/technical/hps/treatment.html
https://www.cdc.gov/hantavirus/hps/symptoms.html
https://wwwnc.cdc.gov/eid/article/3/2/97-0213_article
https://www.ncbi.nlm.nih.gov/pubmed/22787210
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840873/

Tularemia
https://www.cdc.gov/tularemia/statistics/index.html
https://www.cdc.gov/tularemia/faq/index.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257795/
https://www.ncbi.nlm.nih.gov/pubmed/21121232
https://www.ncbi.nlm.nih.gov/pubmed/22911645
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5351a3.htm
https://www.sciencedaily.com/releases/2018/05/180530144123.htm
https://www.nejm.org/doi/10.1056/NEJMoa011374?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dwww.ncbi.nlm.nih.gov
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6247a5.htm
https://emergency.cdc.gov/agent/agentlist-category.asp
https://jamanetwork.com/journals/jama/article-abstract/193894
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207810/
http://aac.asm.org/content/44/12/3428.full

Legionnaire’s disease
https://www.cdc.gov/legionella/about/causes-transmission.html
https://www.cdc.gov/legionella/about/diagnosis.html
https://www.ncbi.nlm.nih.gov/pubmed/22227989
https://www.ncbi.nlm.nih.gov/pubmed/1552203
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048947/
https://www.ncbi.nlm.nih.gov/pubmed/10987244
https://www.ncbi.nlm.nih.gov/pubmed/22465301

Cysticercosis
https://www.cdc.gov/parasites/cysticercosis/health_professionals/index.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347341/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451927/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725874/
https://www.sciencedirect.com/science/article/pii/S0001706X16306507

Amoeba
https://www.cdc.gov/parasites/naegleria/general.html
https://www.ncbi.nlm.nih.gov/pubmed/22238170
https://www.ncbi.nlm.nih.gov/pubmed/25595746
https://www.ncbi.nlm.nih.gov/pubmed/24967566
https://www.ncbi.nlm.nih.gov/pubmed/23708581
https://www.ncbi.nlm.nih.gov/pubmed/25667249
https://www.ncbi.nlm.nih.gov/pubmed/22919000
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627687/
https://www.weather.gov/safety/lightning-fatalities17
https://www.ncbi.nlm.nih.gov/pubmed/17894804

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How to build synthetic DNA and send it across the internet | Dan Gibson

Biologist Dan Gibson edits and programs DNA, just like coders program a computer. But his “code” creates life, giving scientists the power to convert digital information into biological material like proteins and vaccines. Now he’s on to a new project: “biological transportation,” which holds the promise of beaming new medicines across the globe over the internet. Learn more about how this technology could change the way we respond to disease outbreaks and enable us to download personalized prescriptions in our homes.

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When Waking up After Decades Turned out to Be Temporary

Around 1917, an unknown illness dubbed “sleeping sickness” caused people to suffer severe sleepiness and delirium. Some even became paralyzed for decades until a temporary cure was discovered in the 1960s. The story of this illness is tragic but offered new insight into how our brains function.

Hosted by: Brit Garner
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Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
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Dooblydoo thanks go to the following Patreon supporters:
Lazarus G, Sam Lutfi, D.A. Noe, سلطان الخليفي, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, Tim Curwick, charles george, Kevin Bealer, Chris Peters
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Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1073797/
https://www.ncbi.nlm.nih.gov/pubmed/29555881
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291398/
https://www.movementdisorders.org/MDS/About/Movement-Disorder-Overviews/Parkinsons-Disease–Parkinsonism.htm
http://blogs.discovermagazine.com/neuroskeptic/2018/04/15/100-years-encephalitis-lethargica/#.WtODEX8h2Uk
https://academic.oup.com/brain/article/140/8/2246/3970828
https://www.sciencedirect.com/science/article/pii/S0361923006000451
https://psychopharmacologyinstitute.com/cns-receptors/d2-receptors/
https://www.ncbi.nlm.nih.gov/pubmed/25491387
https://books.google.com/books?id=DIMpyllgatAC&printsec=frontcover#v=onepage&q&f=false
https://www.ncbi.nlm.nih.gov/pubmed/25491387
http://jnnp.bmj.com/content/jnnp/35/4/487.full.pdf
https://www.sciencedirect.com/science/article/pii/S0306452214005843
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1471-4159.1991.tb11402.x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC42581/
https://www.ncbi.nlm.nih.gov/pubmed/1825842
https://www.ncbi.nlm.nih.gov/pubmed/14962622
https://academic.oup.com/jnen/article/60/7/663/2916219
https://www.prd-journal.com/article/S1353-8020(07)00208-8/fulltext
http://jnnp.bmj.com/content/jnnp/35/4/487.full.pdf
https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-12-136
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778472/

Image Sources:
https://commons.wikimedia.org/wiki/File:Substantia_Nigra.jpg
https://commons.wikimedia.org/wiki/File:Oliversacks.jpg
https://en.wikipedia.org/wiki/L-DOPA#/media/File:3,4-Dihydroxy-L-phenylalanin_(Levodopa).svg

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Could the Plague Rise Again?

How likely is a 21st-century epidemic of the plague? Unlike other diseases, the plague is alive and well in some parts of the world, but scientists and doctors are continuing to develop better treatments.

Hosted by: Stefan Chin

Head to https://scishowfinds.com/ for hand selected artifacts of the universe!
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Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
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Sources:

http://discovermagazine.com/2001/nov/featblack
https://www.express.co.uk/news/world/874231/Black-death-plague-why-back-Madagascar-outbreak-bubonic-plague-Africa
https://theconversation.com/how-yersinia-pestis-evolved-its-ability-to-kill-millions-via-pneumonic-plague-43989
https://theconversation.com/explainer-what-is-the-plague-29574
https://www.ncbi.nlm.nih.gov/pubmed/10796565
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027722/
https://www.nature.com/articles/ncomms8487
https://www.cell.com/trends/microbiology/abstract/S0966-842X(15)00273-5
https://ourworldindata.org/eradication-of-diseases
http://www.bbc.com/news/magazine-34398099 (nasty pictures)
https://www.futurity.org/plague-yersinia-pestis-854072/
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004587
https://www.nature.com/articles/ncomms8487
https://www.smithsonianmag.com/smithsonian-institution/ask-smithsonian-world-due-another-massive-plague-outbreak-180957001/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155008/
http://blogs.discovermagazine.com/notrocketscience/2008/10/23/the-secret-of-drug-resistant-bubonic-plague/
https://www.npr.org/sections/goatsandsoda/2017/10/04/555338600/why-plague-season-is-a-big-worry-in-madagascar-this-year
https://www.nytimes.com/2017/10/06/health/madagascar-plague.html
http://aac.asm.org/content/50/10/3233.full
https://www.cdc.gov/plague/transmission/index.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256048/

Images:

https://commons.wikimedia.org/wiki/File:Boccaccio%27s_%27The_plague_of_Florence_in_1348%27_Wellcome_L0072143.jpg
https://commons.wikimedia.org/wiki/File:Yersinia_pestis.jpg
https://commons.wikimedia.org/wiki/File:Rattenfloh_inf.jpg
http://www.thinkstockphotos.com/image/stock-photo-lymphatic-system/115918390
http://www.thinkstockphotos.com/image/stock-photo-3d-illustration-of-heart-medical-concept/805427734
http://www.thinkstockphotos.com/image/stock-photo-3d-illustration-of-lungs-medical-concept/805552952
https://commons.wikimedia.org/wiki/File:Flea_Scanning_Electron_Micrograph_False_Color.jpg
https://commons.wikimedia.org/wiki/File:The_black_death._Watercolour_by_Monro_S._Orr._Wellcome_V0017196.jpg
https://commons.wikimedia.org/wiki/File:Doutielt3.jpg

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