The Best Ways to Keep Your Mind Young

You might feel like your thinking has been getting a bit slower and foggier as you get older, and that eventually happens to everybody. But how can we keep our minds young?

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Can We Get Older Without Aging?

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Nothing is guaranteed in life except death, taxes, and entropy. What do other life forms have to teach us about staying alive as we get old, and will we ever conquer death?

REFERENCES:

Arias, E. et al. (2013). United States life tables eliminating certain causes of death, 1999–2001. National Vital Statistics Reports 61(9)

De Cecco, M. et al. (2013). Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues. Aging 5(12): 867–883. DOI: 10.18632/aging.100621

Hayflick, L. (2016). Unlike aging, longevity is sexually determined. In Handbook of theories of aging, 3rd ed. (pp. 31-52). New York, NY, Springer.

Hayflick, L. (UCSF School of Medicine). Interview.

Klapper, W. et al. (1998). Longevity of lobsters is linked to ubiquitous telomerase expression. FEBS Letters 439: 143-146

Martinez, D.E. (1998). Mortality patterns suggest lack of senescence in hydra. Experimental Gerontology 33(3): 217–225

Reilly, M.T. et al. (2013). The role of transposable elements in health and diseases of
the central nervous system. The Journal of Neuroscience 33(45): 17577–17586

Roth, A.W. and Polotsky, A.J. (2012). Can we live longer by eating less? A review of caloric restriction and longevity. Maturitas 71: 315–319

Sturm, A. et al. (2015). The mechanism of ageing: primary role of transposable elements in genome disintegration. Cell. Mol. Life Sci. 72:1839–1847

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Sorry, I’m a Slow Eater

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How UV Causes Cancer and Aging

UV at ground level is non-ionizing but it damages DNA and causes photoaging – how?
Also, it turns out glass doesn’t block all UV (specifically UVA passes through). This is something I learned filming with the UV camera inside.

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Ultraviolet light causes damage to DNA, leads to cancer and photoaging: age spots and wrinkles. I was curious about this because UV is technically non-ionizing. A photon of UV doesn’t have enough energy to strip an electron off atoms or molecules. However it does have enough energy to trigger photo-chemical reactions. For example, it causes pyrimidine dimers – the unauthorized covalent bonding of adjacent thymine or cytosine bases in our DNA. If these spots are not properly repaired, they may lead to mutations and cancer. Photoaging is typically the result of degradation of collagen and elastin fibers – scaffolding that supports the skin. This leads to wrinkles and saggy-looking skin.

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The Real Reason You’re Always Losing Your Keys

Do you often lose things like your keys? Psychology can explain not only why it happens, but also some ways to combat that.

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Sources:
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Image Source:
https://en.wikipedia.org/wiki/Dopamine_receptor_D2#/media/File:Protein_DRD2_PDB_1I15.png

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